If a person has celiac disease, their body produces autoantibodies targeting self-antigens. 

LifeLabs offers a combination of two tests to aid in celiac disease diagnosis and monitoring:

•  Anti TTG IgA
• Anti Deamidated Gliadin IgG

While tTG IgA is the primary antibody produced in individuals with celiac disease, some people have an IgA deficiency which produces a false negative result. LifeLabs tTG IgA test automatically assesses IgA concentration to minimize the risk of false negatives, To aid in diagnosis and monitoring of IgA deficient patients, LifeLabs offers deamidated gliadin IgG antibody test as an alternate test.

Additional information can be found in our Celiac Test brochure here.

You can be tested for celiac disease at any age. The symptoms are often nonspecific and variable, making the disease difficult to spot. You should speak with your doctor if you have a family history of celiac disease, or if you are experiencing one or more of the symptoms commonly associated with celiac disease including:

• abdominal pain and bloating
• chronic diarrhea
• weight loss
• extreme fatigue
• flatulence
• unexplained iron-deficiency anemia
• joint pain

You can order the test here.

A physician may recommend a celiac blood test if you:

• are exhibiting symptoms common associated with celiac disease
• have a medical history that suggests celiac disease is a possibility
• have a family history of celiac disease
• have already been diagnosed with celiac disease and physician wants to monitor your tTG IgA and/or deamidated gliadin IgG antibody levels after gluten has been removed from your diet

A physician may also order a test if you have a condition that is known to be associated with celiac disease including:

• Type 1 diabetes
• Down syndrome
• Thyroiditis
• Arthritis
• Depression
• Neuropathy

Testing is completed by LifeLabs at a Patient Service Centre or via our mobile lab service (available in select cities) through a simple blood sample. You will require a completed test requisition from your healthcare provider.

You can order the test here.

Test results will be provided directly to your healthcare provider for discussion with you. The report will indicate:

• Whether tTG IgA protein is present in your blood and the levels
• Whether deamidated gliadin IgG protein is present in your blood and the levels

If your test results show the presence of either the tTG IgA or deamidated gliadin IgG antibodies, your healthcare provider may suggest additional testing before developing a treatment plan.

Sources