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Fertility Test
Fertility Test

Anti-Müllerian Hormone (AMH)

With one in six couples across Canada experiencing difficulty in becoming pregnant, AMH levels can provide valuable insight into predicting a response for IVF treatment.

How is the test performed?

Blood sample

When will I get my results?

Results are available to your healthcare provider within two weeks.

The anti-Müllerian hormone (AMH) is a protein produced by granulosa cells in ovarian follicles. AMH levels tend to be at the highest around the age of 25 and then begin to decline after the age of 30. The level of AMH in the blood stream can be an indicator of fertility in women, specifically in relations to the number of eggs in reserve in the ovaries. It can also help to predict menopause and diagnosis ovarian hyperstimulation syndrome and polycystic ovary syndrome.

An AMH test is a blood test used to measure AMH levels circulating in your body. There is a relationship between AMH levels and fertility levels in women. The higher the AMH level, the higher the number of eggs.

Measuring AMH levels can help to:
  • evaluate ovarian reserve (number of eggs)
  • predict likelihood of IVF success
  • predict the age of menopause
  • confirm diagnosis of premature ovarian failure
  • assess the risk of ovarian hyperstimulation syndrome (OHSS)
  • diagnose polycystic ovary syndrome (PCOS).

If you are a woman experiencing difficulty becoming pregnant and considering invitro fertilization treatment (IVF), you should speak to your healthcare provider about whether an AMH test is right for you.

Your healthcare provider may also order an AMH test if they are concerned about:
  • the onset of menopause
  • ovarian hyperstimulation syndrome (OHSS)
  • polycystic ovary syndrome (PCOS).

 

The AMH test is commonly ordered for:

  • women experiencing difficulty getting pregnant
  • women considering undergoing IVF treatment
  • diagnosing polycystic ovary syndrome (PCOS)
  • diagnosing ovarian hyperstimulation syndrome (OHSS)
  • predicting the age of menopause

Testing is completed by LifeLabs at a Patient Service Center or via our mobile lab service through a simple blood sample. You will require a completed test requisition from your healthcare provider.

Test results will be provided directly to your doctor for discussion with you. The report will indicate:

  • AMH levels circulating in your blood
  • Range levels for AMH levels

Your medical history, age and other factors influence the outcome of the tests. Your doctor will help explain the results and determine whether further testing or treatment is required.

High AMH levels can indicate:
  • a higher the number of remaining ovarian follicles (eggs)
  • a higher likelihood in positive response to IVF
  • polycystic ovary syndrome
A decline in AMH levels can reflect a number of items including:
  • a progression to menopause
  • a lower likelihood of positive response to IVF
  • ovarian hyperstimulation syndrome (OHSS).

Sources

  • Health Canada
  • Broer SL, Broekmans FJ, Laven JS, and Fauser BC. Anti-Müllerian hormone: ovarian reserve testing and its potential clinical implications. Hum Reprod Update 2014;20:688-701.
  • Dewailly D, Andersen CY, Balen A et al. The physiology and clinical utility on anti-Müllerian hormone in women. Hum Reprod Update 2014;20:370-385
  • Green JA, and Graves G. Is there a place for AMH testing in Canada? J Obstet Gyneacol Can 2011;33:628-632.
  • Ledger WL. Clinical utility of measurement of anti-Müllerian hormone in reproductive endocrinology. J Clin Endocrinol Metab 2010;95:5144-5154.
  • Iliodromiti S, Kelsey TW, Anderson RA et al. Can anti-Müllerian hormone predict the diagnosis of polycystic ovary syndrome? A systematic review and meta-analysis of extracted data. J Clin Endocrinol Metab 2013;98:3332-3340.

​​Anti-Müllerian hormone (AMH) is a protein produced by granulosa cells in ovarian follicles. A blood test for AMH is most commonly used to assess the reserve of ovarian follicles and to predict response to controlled ovarian stimulation during in vitro fertilization (IVF).

AMH levels circulating in blood may be used to:
  • predict age of menopause
  • confirm diagnosis of premature ovarian failure
  • predict likelihood of IVF success. (AMH levels correlate positively with number of retrieved oocytes1 and low AMH levels predict a lower likelihood of follicle response.)
  • assess risk of ovarian hyperstimulation syndrome (OHSS) caused by exaggerated response to gonadotropin treatment 
  • help diagnose polycystic ovary syndrome (PCOS). 

​Samples for AMH testing may be taken at any of our Patient Service Centres. Healthcare provider needs to indicate ‘AMH’ in the ‘Other Tests’ section of the requisition form.

 

The AMH test is currently an uninsured test. The cost is: $70

Payment may be made by the patient when the blood sample is taken at one of our Patient Service Centres. For convenience, Visa, Mastercard and Debit Cards are excepted.

Patient are encouraged to check with their private health care provider to see if coverage is provided.

Results will be available to you within two weeks.

We have a wealth of medical experts available to support you in interpreting test results.
Consults with our experts are available upon request. Request medical consultation.

Request more information

An AMH test may be scheduled directly by the patient at any of our Patient Service Centres offering this service. They must have a requisition form completed by a physician or healthcare provider.

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