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LifeLabs supports over 19 million patient visits annually, performing over 100 million tests.
LifeLabs is Canada’s largest community laboratory testing services provider.
Panorama is a Non-Invasive Prenatal Test (NIPT) that screens for common genetic conditions caused by extra or missing chromosomes in the baby’s DNA as early as 9 weeks. Panorama analyzes baby's (placental) DNA through a simple blood draw from the mother’s arm.
Panorama screens for the most common genetic conditions and sequences only those chromosomes of interest (13, 18, 21, X and Y). Some conditions, such as Down syndrome, are caused by extra or missing copies of a specific chromosome. Others genetic conditions, such as microdeletions, occur when a chromosome is missing a small piece of genetic information. Microdeletions affect women equally, regardless of age, whereas the chance of a chromosome abnormality increases with a woman’s age.
The Panorama prenatal screen is designed for women of any age and ethnicity who are at least 9 weeks pregnant. It cannot currently be used by women who are carrying more than one baby (twins or triplets), women who have used a donor egg or a surrogate, or those who have received a bone marrow transplant.
Panorama can be performed as early as 9 weeks into the pregnancy and all the way up to the end of pregnancy
As early as 9 weeks into your pregnancy, a simple blood draw can tell you if your baby is at higher risk for having Down syndrome and other common genetic conditions. Panorama sequences only those chromosomes of interest (13, 18, 21, X, and Y) using single-nucleotide polymorphisms (SNPs). Panorama’s SNP methodology is accurate at fetal fractions (ff) as low as 2.8% and can be used earlier in pregnancy. Panorama® is the only NIPT that can differentiate between maternal and fetal DNA, resulting in the highest accuracy for the chromosomes of interest. Non-invasive and highly accurate, Panorama identifies more than 99% of pregnancies affected with Down syndrome and has the lowest reported false positive rate of any prenatal screening test for the commonly screened chromosomal abnormalities: trisomy 21, trisomy 18, and trisomy 13. The Panorama® method is also the only one able to detect triploidy. Panorama’s high sensitivity (>99%) and low false-positive rate (<0.1%) can reduce the number of unnecessary invasive diagnostic procedures, like chorionic villus sampling (CVS) and amniocentesis, which carry a risk of miscarriage.
Panorama is able to determine the likelihood that the pregnancy could be affected with chromosome abnormalities including Down syndrome (trisomy 21), trisomy 18, trisomy 13, monosomy X and triploidy. Your healthcare provider may also recommend additional chromosomal conditions (microdeletions) be screened for using Panorama. Microdeletion conditions on Panorama’s extended panel include 22q11.2 deletion syndrome, 1p36 deletion, Cri-du-chat syndrome, Prader-Willi syndrome and Angelman syndrome. While it is not the sole purpose of the test, the baby’s gender information can also be screened for using Panorama. Panorama does not screen for all possible birth defects and genetic diseases, such as open neural tube defects. Speak to your physician if you have special concerns due to family history or other factors.
The report will be sent to your ordering healthcare provider and may state the following:
Click here to find out more about Chromosome Abnormalities.
The Panorama test uses a maternal blood sample.
*Some provincial health plans may cover the cost of Panorama, so speak with your healthcare provider or contact LifeLabs Genetics. As well, some personal medical insurance plans may cover the cost of the test. Check with your carrier.
Results will be available within 7-10 calendar days once the lab receives your sample.
The American College of Obstetricians and Gynecologists is recommending non-invasive prenatal screening (NIPT) for all pregnant women regardless of age or other risk factors as the initial option to screen for genetic conditions, such as Trisomy 21 (Down syndrome) during pregnancy.
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