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Reproductive Health


Panorama is a Non-Invasive Prenatal Test (NIPT) that screens for common genetic conditions caused by extra or missing chromosomes in the baby’s DNA as early as 9 weeks. Panorama analyzes baby's (placental) DNA through a simple blood draw from the mother’s arm.


What does Panorama test for?

Panorama screens for the most common genetic conditions and sequences only those chromosomes of interest (13, 18, 21, X and Y). Some conditions, such as Down syndrome, are caused by extra or missing copies of a specific chromosome. Others genetic conditions, such as microdeletions, occur when a chromosome is missing a small piece of genetic information. Microdeletions affect women equally, regardless of age, whereas the chance of a chromosome abnormality increases with a woman’s age.

Who should have Panorama prenatal screen?

The Panorama prenatal screen is designed for women of any age and ethnicity who are at least 9 weeks pregnant. It cannot currently be used by women who are carrying more than one baby (twins or triplets), women who have used a donor egg or a surrogate, or those who have received a bone marrow transplant.

When Should I have Panorama prenatal screen?

Panorama can be performed as early as 9 weeks into the pregnancy and all the way up to the end of pregnancy

What are the benefits of having the Panorama prenatal screen?

As early as 9 weeks into your pregnancy, a simple blood draw can tell you if your baby is at higher risk for having Down syndrome and other common genetic conditions. Panorama sequences only those chromosomes of interest (13, 18, 21, X, and Y) using single-nucleotide polymorphisms (SNPs). Panorama’s SNP methodology is accurate at fetal fractions (ff) as low as 2.8% and can be used earlier in pregnancy. Panorama® is the only NIPT that can differentiate between maternal and fetal DNA, resulting in the highest accuracy for the chromosomes of interest. Non-invasive and highly accurate, Panorama identifies more than 99% of pregnancies affected with Down syndrome and has the lowest reported false positive rate of any prenatal screening test for the commonly screened chromosomal abnormalities: trisomy 21, trisomy 18, and trisomy 13. The Panorama® method is also the only one able to detect triploidy. Panorama’s high sensitivity (>99%) and low false-positive rate (<0.1%) can reduce the number of unnecessary invasive diagnostic procedures, like chorionic villus sampling (CVS) and amniocentesis, which carry a risk of miscarriage.

What should I be screened for?

Panorama is able to determine the likelihood that the pregnancy could be affected with chromosome abnormalities including Down syndrome (trisomy 21), trisomy 18, trisomy 13, monosomy X and triploidy. Your healthcare provider may also recommend additional chromosomal conditions (microdeletions) be screened for using Panorama. Microdeletion conditions on Panorama’s extended panel include 22q11.2 deletion syndrome, 1p36 deletion, Cri-du-chat syndrome, Prader-Willi syndrome and Angelman syndrome. While it is not the sole purpose of the test, the baby’s gender information can also be screened for using Panorama. Panorama does not screen for all possible birth defects and genetic diseases, such as open neural tube defects. Speak to your physician if you have special concerns due to family history or other factors.

How are results reported?

The report will be sent to your ordering healthcare provider and may state the following:

  • Low Risk: indicates that there is a very low chance that your baby is affected by one of the conditions on the Panorama panel.
  • High Risk: does not mean the baby is affected; rather, it indicates a higher than average chance that the baby has a chromosome abnormality. In the event of a High Risk result, the ordering physician will be contacted by a board-certified genetic counsellor at LifeLabs. Your healthcare provider is likely to recommend that you speak with a genetic counsellor and or maternal fetal medicine specialist. You may be offered invasive diagnostic testing such as amniocentesis or CVS. No irreversible pregnancy decisions should ever be made based on a Panorama result alone.
  • No Result: in a small percentage of cases, Panorama may not be able to obtain sufficient information from your blood sample to determine an accurate result. If this occurs, a second blood sample may be requested.

What are Chromosome Abnormalities?

Click here to find out more about Chromosome Abnormalities.

How is the test performed?

The Panorama test uses a maternal blood sample.

How much does it cost?

  • Panorama Prenatal test – $550.00
  • 22q11.2 Deletion syndrome – additional $195.00
  • Microdeletion extended panel – additional $245.00

*Some provincial health plans may cover the cost of Panorama, so speak with your healthcare provider or contact LifeLabs Genetics. As well, some personal medical insurance plans may cover the cost of the test. Check with your carrier.

When will I get my results?

Results will be available within 7-10 calendar days once the lab receives your sample.

How to Order

Did you know?

The American College of Obstetricians and Gynecologists is recommending non-invasive prenatal screening (NIPT) for all pregnant women regardless of age or other risk factors as the initial option to screen for genetic conditions, such as Trisomy 21 (Down syndrome) during pregnancy.

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